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多发性硬化(multiple sclerosis,MS)是累及中枢神经系统白质的炎性脱髓鞘疾病,目前病因尚不完全明确,一般认为与遗传、环境与免疫等因素有关[1]。MS是导致中青年非外伤性致残的常见原因之一,给家庭和社会均带来沉重的负担。随着近年神经科学的发展,MS患者认知功能损害已越来越引起医生的关注。研究表明,MS患者认知障碍发病率为40%~65%[2,3]。MS患者认知功能损害主要包括延迟记
Multiple sclerosis (MS) is an inflammatory demyelinating disease involving the white matter of the central nervous system. At present, the cause of the disease is not completely clear, and is generally considered to be related to factors such as genetics, environment and immunity [1]. MS is one of the common causes of non-traumatic disability in young and middle-aged, which brings a heavy burden to families and society. With the development of neuroscience in recent years, cognitive impairment in MS patients has drawn more and more attention of doctors. Research shows that the incidence of cognitive impairment in MS patients is 40% to 65% [2,3]. Cognitive impairment in MS patients mainly includes delayed memory