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为了确定胃癌术后感染并发症(肺炎,尿路感染,创口感染,局限性、弥漫性化脓性腹膜炎及菌血症)是否与输血有关,作者等对1985～1989年全部胃癌手术患者196例进行回顾性研究。71例(36.2%)发生术后感染并发症,这些患者自住院至出现感染接受总的输血量平均为4.2单位,与未发生术后感染并发症患者(接受总的输血量平均为2.7单位)相比,两者有显著差异(P<0.0053)。此外,尚发现输血与术后发生感染危险之间存在着量-反应关系,得到Mantel-Haenszel 试验证实。逻辑回归分析也显示与手术前抗生紊预防(P<0.015),尿路插管(P<0.002)及手术持续时间(P<0.027)一样,输血对发生术后感染也是一个独立的危险因素(P<0.01)。上述显著性差异都是经过精确数学分析排除了年龄、性别、出现症状时间、术前感染情况、诊断时白细胞数、血红蛋白水平及总蛋白量、肿瘤部
In order to determine whether postoperative infection complications of gastric cancer (pneumonia, urinary tract infections, wound infections, limitations, diffuse pyogenic peritonitis, and bacteremia) are related to blood transfusion, the authors performed 196 cases of total gastric cancer patients from 1985 to 1989. Retrospective study. Postoperative infection complications occurred in 71 patients (36.2%). The average transfusion volume of these patients from admission to infection was 4.2 units in average. Patients with no postoperative infection complications (average total blood transfusion volume was 2.7 units). In comparison, there was a significant difference between the two (P<0.0053). In addition, a quantitative-response relationship between blood transfusion and the risk of postoperative infection has been found and confirmed by the Mantel-Haenszel test. Logistic regression analysis also showed that blood transfusion was an independent risk factor for the occurrence of postoperative infections, as well as preoperative antagonism (P<0.015), urinary catheterization (P<0.002), and duration of surgery (P<0.027). P<0.01). The above-mentioned significant differences were all after precise mathematical analysis that ruled out age, gender, time of onset of symptoms, preoperative infection, number of white blood cells at diagnosis, hemoglobin level and total protein amount, and tumor department.