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目的探讨术中组织印片细胞DNA倍体分析在乳腺病变诊断中的价值,提高术中快速诊断的准确率。方法对220例乳腺术中冷冻标本进行术中组织印片细胞DNA倍体分析及冷冻切片诊断,并与术后石蜡切片诊断对比分析。结果 220例乳腺肿块术中冷冻切片确诊213例(96.8%);术中组织印片细胞DNA倍体分析确诊217例(98.6%);二者联合确诊218例,确诊率为99.1%。结论将冷冻切片联合组织印片细胞DNA倍体分析应用于乳腺肿块术中快速病理检查,可以减少误诊,提高快速诊断的准确性。
Objective To investigate the value of intraoperative tissue photofluorescence DNA ploid analysis in the diagnosis of breast lesions and to improve the accuracy of intraoperative rapid diagnosis. Methods 220 cases of intraoperative breast frozen tissue specimens were printed tissue cells DNA ploid analysis and frozen section diagnosis, and postoperative paraffin section diagnosis comparative analysis. Results Two hundred and seventy cases of breast masses were diagnosed by cryosurgery in 213 cases (96.8%). Totally 217 cases (98.6%) were diagnosed by DNA ploidy in the tissue samples. The combined diagnosis of 218 cases was 99.1%. Conclusion The application of cryopreservation combined with tissue photofinishing cell DNA ploid analysis in rapid pathological examination of breast lumps can reduce misdiagnosis and improve the accuracy of rapid diagnosis.