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目的:观察宽叶缬草对家兔心率和血压的影响。方法:记录Ⅱ导联心电图观察心率和心电图波型的变化,左颈总动脉插管记录家兔的动脉血压。结果:应用宽叶缬草后,心率降低,心电图ST段和T波持续时间延长,血压降低,以舒张压降低为主,此作用呈剂量依赖性,其可降低肾上腺素引起的心率加快和血压升高作用。结论:宽叶缬草能降低家兔的心率和血压。
Objective: To observe the effects of Valeriana officinalis on heart rate and blood pressure in rabbits. METHODS: The II-lead electrocardiogram was used to observe changes in heart rate and electrocardiogram waveforms. The left common carotid artery was cannulated to record arterial blood pressure in rabbits. RESULTS: After the application of broadleaf weeds, the heart rate decreased, the duration of ST segment and T wave of electrocardiogram was prolonged, blood pressure decreased, and the diastolic blood pressure decreased. This effect was dose-dependent, which could reduce the adrenal heart rate acceleration and blood pressure. Raise the effect. Conclusion: Valeriana can reduce heart rate and blood pressure in rabbits.