铝是地壳中含量最丰富的金属元素之一，广泛存在于周围环境及日常生活中。铝为人体的非必需元素，长期蓄积可影响人体的多个系统器官的功能。近年来，铝对人体健康影响的报道日渐增多，其中铝对免疫系统功能影响的相关研究也越来越受到关注。铝可通过不同的机制对免疫系统中T淋巴细胞和B淋巴细胞等产生影响，且随着铝暴露的剂量、时间、方式、合并的基础疾病不同，影响也不同。“,”Aluminum,one of the most abundant metal elements in the earth′s crust,is widely found in our surrounding environment and daily life.Aluminum is the non-essential elements of human body and the long-term accumulation may affect function of many systems and organs .In recent years,the impact of alumi-num on the body has got lots of attention,including the immune system.Aluminum can affect function of T and B lymphocytes through different mechanisms,which varies accordingly with the exposure amount,time, manner and the basic diseases of the patietns.