本文报告45例肺局限性病变,经常规检查方法未能确诊的病人,采用经胸针吸活检术进行诊断的方法及结果。病变结节最小3厘米。用改制的穿刺针在X射线透视或电视增强透视引导下,50次针吸的细胞学结果为;一次针吸恶性细胞阳性率为90％,二次累计阳性率为93.3％。良性病变符合率为93.3％。假阴性1例。并对本法的适应症及禁忌症作了讨论。 In this paper, 45 patients with localized pulmonary lesions and those who have not been diagnosed by routine examinations have been treated with transthoracic needle biopsy for diagnosis. The lesion nodules a minimum of 3 cm. The cytological results of 50 needles under the guidance of X-ray fluoroscopy or TV-enhanced fluoroscopic guidance with a modified puncture needle were as follows: The positive rate of malignant cells in one needle was 90%, and the second cumulative positive rate was 93.3%. The rate of benign lesions was 93.3%. One false negative case. It also discussed the indications and contraindications of this law.