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目的探讨继发不育男性患者泌尿生殖系支原体的感染状况及其耐药性。方法采用支原体分离培养鉴定与药敏试剂盒,对继发不育男性患者泌尿生殖系分泌物进行支原体分离培养鉴定与药敏测试。结果572例继发不育男性患者,泌尿生殖系支原体培养阳性278例,阳性率为48.6%,其中Uu占90.3%(251/278);Mh占1.4%(4/278);Uu合并Mh占8.3%(23/278)。药敏试验表明:喹诺酮类耐药率最高,四环素类和大环内酯类耐药率最低。结论支原体感染是男性继发不育的重要危险因素,在支原体感染的治疗过程中,我们应根据药敏测试结果选择敏感抗生素。
Objective To investigate the infection status and drug resistance of genitourinary mycoplasma in patients with secondary infertility. Methods Mycoplasma isolates were identified by culture and drug susceptibility test kit. Mycoplasma isolates from male with infertility were identified by mycoplasma and drug sensitivity test. Results Among 572 cases of infertile men, genitourinary mycoplasma was positive in 278 cases, the positive rate was 48.6%, of which, Uu accounted for 90.3% (251/278); Mh accounted for 1.4% (4/278); Uu combined Mh 8.3% (23/278). Susceptibility tests showed that the highest quinolone resistance rate, the lowest tetracycline and macrolide resistance rates. Conclusion Mycoplasma infection is an important risk factor for male infertility. During the treatment of mycoplasma infection, we should select sensitive antibiotics according to the results of susceptibility testing.