四氯化钛(TiCl_4)是制备金属钛的重要原料,在生产现场和环境中以烟雾形式存在,具有强烈的刺激性和腐蚀性,对机体的损害多为表皮和呼吸系统粘膜的刺激症状。有关TiCl_4的致突变性研究甚少,为保护生产工人的安全和特殊防护提供依据,本文进行了较为系统的研究。一、微核试验:将体重20～25克的昆明种(下同)小白鼠50只,每组10只(雌雄各半),置入有机玻璃 Titanium tetrachloride (TiCl 4) is an important raw material for the preparation of titanium. It exists in the form of smoke in the production site and in the environment. It is strongly irritant and corrosive. Most of the damage to the body is the irritation of the epidermis and respiratory mucosa. There is little research on the mutagenicity of TiCl_4, which provides a basis for the protection of the safety and special protection of production workers. This article has carried out a systematic study. First, the micronucleus test: The body weight of 20 to 25 grams of Kunming (the same below) mice 50, each group of 10 (male and female half), into the plexiglass