１９９６年２～７月，广东省大部分地区发生流感流行，暴发点集中在中、小学和幼儿园。此次流行特点包括，（１）流感病毒甲３型流行，优势毒株呈“Ｏ”相生物学性状；（２）流行高峰在４、５月，无明显夏季流行峰；（３）流行地区广泛，波及区域主要在人口集中的全省大、中城市及其附近地区；（４）呈学校型暴发，罹患者多为青少年及婴幼儿。针对目前流感抗原变异导致流感流行的现状，建议加强流感监测工作，尤其在流行季节的人群集中生活场所；同时采用流感疫苗免疫接种易感人群，尤其是对儿童和老龄人。 From February to July 1996, a pandemic occurred in most parts of Guangdong Province. The outbreaks were concentrated in primary and secondary schools and kindergartens. The epidemic characteristics include: (1) influenza A type 3 epidemic, the dominant strains are “O” phase biological characteristics; (2) the peak of the epidemic in April and May, no significant summer peak; (3) endemic areas The widespread and affected areas are mainly concentrated in large and medium-sized cities in the province and its vicinity; (4) School-based outbreaks are mostly occurred in adolescents and infants. In view of the current status of influenza epidemic caused by influenza antigen variation, it is suggested to strengthen the surveillance of influenza, especially in the concentrated season of the population, and at the same time the influenza vaccine should be used to immunize susceptible people, especially children and the elderly.