论文部分内容阅读
目的:探讨淋巴细胞计数对脓毒症患者预后的评估价值。方法:回顾性收集2017年7月至2019年6月入住郑州大学第五附属医院重症医学科符合诊断标准的患者231例，根据28 d预后情况分为生存组(117例)和死亡组(114例)；再根据确诊脓毒症后24 h内淋巴细胞计数分为≤0.50×10n 9/L组(A组，71例)，(0.50～1.00)×10n 9/L组(B组，70例)和≥1.00×10n 9/L组(C组，89例)。收集患者的性别、年龄、引起脓毒症的原发感染灶、确诊脓毒症24 h内序贯器官衰竭估计评分(SOFA评分)、淋巴细胞计数以及预后等指标。n 结果:生存组患者SOFA评分低于死亡组、淋巴细胞计数高于死亡组，差异均有统计学意义(n P均<0.05)。A组患者生存率低于B、C组，生存时间短于B、C组，差异均有统计学意义(n P均0.05)。A组患者28 d的死亡风险高于B、C组(n P0.05)。n 结论:淋巴细胞计数可以用于脓毒症患者临床预后的评估，淋巴细胞计数≤0.50×10n 9/L的脓毒症患者其死亡风险显著增加。n “,”Objective:To observe the value of lymphocyte count in predicting the prognosis of patients with sepsis.Methods:A total of 231 patients with sepsis were retrospectively collected from July 2017 to June 2019 in Intensive Care Unit of the Fifth Affiliated Hospital of Zhengzhou University. According to the 28-day prognosis, they were divided into survival group (117 cases) and death group (114 cases); according to the lymphocyte count within 24 hours after diagnosis of sepsis, they were divided into ≤ 0.50×10n 9/L group (group A, 71 cases), group B (0.50 - 1.00)×10n 9/L group (group B, 70 cases) and ≥1.00×10n 9/L group (group C, 89 cases). The gender, age, sequential organ failure assessment(SOFA)score, lymphocyte count, site of infection causing sepsis and prognosis were collected.n Results:The SOFA score of survival group was lower than that of death group, and lymphocyte count was higher than that of death group (n P<0.05). The survival rate of group B was lower than that of group B and group C (n P<0.05). The 28-day mortality risk of group A was higher than that of group B and C (n P0.05).n Conclusions:Lymphocyte count can be used to evaluate the clinical prognosis of patients with sepsis. The risk of death in patients with sepsis with lymphocyte count ≤0.50 × 10n 9/L is significantly increased.n