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目的:了解时辰化疗联合耳穴敷贴及中药浴足治疗对非小细胞肺癌患者淋巴细胞亚群的影响。方法:选择96例非小细胞肺癌患者,随机分为A组:时辰化疗联合耳穴敷贴、中药浴足组;B组:时辰化疗组;C组:常规化疗组,按照预定方案治疗两周期,于治疗前和治疗后取外周血,采用流式细胞术测淋巴细胞亚群,观察患者治疗前后免疫功能变化情况。结果:A组外周血CD3+、CD4+、CD3-CD19+淋巴细胞亚群治疗后较治疗前显著升高;治疗后A组的CD3+、CD4+、CD3-CD19+淋巴细胞亚群较B组、C组显著升高。结论:时辰化疗联合耳穴敷贴、中药浴足治疗非小细胞肺癌较时辰化疗及常规化疗能显著提高患者免疫功能。
Objective: To understand the effect of temporal chemotherapy combined with auricular acupuncture and herbal bathing on lymphocyte subsets in patients with non-small cell lung cancer. Methods: Ninety-six patients with non-small cell lung cancer (NSCLC) were randomly divided into three groups: group A with chrono-chemotherapy combined with auricular acupoint application and Chinese herbal bathing group; group B with chrono-chemotherapy group; group C with conventional chemotherapy group, Peripheral blood samples were taken before and after treatment. The lymphocyte subsets were detected by flow cytometry and the changes of immune function before and after treatment were observed. Results: After treatment, the levels of CD3 +, CD4 + and CD3-CD19 + lymphocyte subsets in peripheral blood of group A were significantly higher than those before treatment. After treatment, the numbers of CD3 +, CD4 +, CD3 + CD19 + lymphocytes in group A were significantly higher than those in group B and C high. Conclusion: Time chemotherapy combined with auricular application of traditional Chinese medicine bath foot treatment of non-small cell lung cancer than chemotherapy and conventional chemotherapy can significantly improve immune function.