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[目的]探讨卵巢交界性浆液性肿瘤(S-BOT)微乳头型与经典类型的组织及临床病理学特征。[方法]收集27例S-BOT病例,结合相关文献对其进行重新分型,并分析不同亚型肿瘤的组织与临床病理学特征。[结果]经重新评估后,7例被归入微乳头型组,20例被归入经典类型组。两组病例在年龄、单双侧、肿瘤局部是否有自然破裂、肿瘤表面是否有新生物及镜下盆腹膜种植、可见砂粒体及淋巴结受累均无明显差异(P>0.05),但微乳头型组瘤体较经典类型组小(P<0.05),在镜下有着可区分的组织学特征,7例微乳头型者均具有>5mm的连续性特殊微乳头状结构区;该微乳头长度是其宽度的5倍或5倍以上,几乎不具有支持性纤维轴心;有时可见筛状结构与微乳头混合存在。而经典类型S-BOT的乳头为粗大的乳头,并有典型的水肿性纤维血管轴心,乳头旁散在与乳头表面细胞相似的细胞巢团。[结论]与经典类型S-BOT相比,微乳头型S-BOT具有独特的、镜下可辨识的微乳头结构,诊断主要基于镜下特殊的形态特点及其>5mm的连续范围。
[Objective] To explore the histopathological and histopathological features of the micro-papillary and classic types of borderline serous ovarian tumors (S-BOT). [Methods] Twenty-seven S-BOT cases were collected and re-typed according to the relevant literature. The histological and clinicopathological features of different subtypes of tumors were analyzed. [Results] After re-evaluation, 7 cases were classified as micropapillary group, 20 cases were classified as classic type group. There was no significant difference between the two groups (P> 0.05) in the age, unilateral and bilateral, whether the tumor had a natural rupture, whether the tumor had a neoplasm and pelvic peritoneal implantation, The tumor group was smaller than the classic type group (P <0.05), with distinguishable histological features under microscopy, and all seven of the patients with micro-nipple type had a> 5mm continuous micro-papilla area. The micro-nipple length was Its width of 5 times or more than 5 times, almost no supportive fiber axis; sometimes visible sieve-like structure and micro-nipple mixed existence. The classic type S-BOT nipple is a thick nipple, and a typical edema of the vascular axis, the nipple next to the surface of the nipple cells in the cell nest. [Conclusion] Compared with the classic S-BOT, the S-BOT has a unique and microscopically identifiable micro-nipple structure. The diagnosis is mainly based on the special microscopic features and the continuous range of> 5mm.