报告１２例癫痫患者苯妥英钠中毒的临床表现与血清药物浓度的关系，１２例患者全部因超量应用苯妥英钠而致头晕、恶心、共济失调等明显临床症状，血药浓度亦超出了正常范围。提出由于苯妥英钠的非线性动力学原因，临床用药应谨慎。苯妥英钠急性中毒所致的小脑损害，大部分病例是可以恢复的 12 cases of epilepsy patients reported clinical manifestations of phenytoin poisoning and the relationship between serum drug concentrations, all of 12 patients due to overdose of phenytoin sodium dizziness, nausea, ataxia and other obvious clinical symptoms, plasma concentrations also beyond the normal range . It is suggested that due to the non-linear kinetics of phenytoin sodium, clinical medication should be cautious. Most cases of cerebellar damage caused by acute poisoning of phenytoin can be recovered