铅是造成环境污染的重金属之一。本实验研究了铅对巨噬细胞免疫吞噬作用的影响。本实验发现铅离子浓度达到10~(-5)以上时,肺巨噬细胞的免疫吞噬活性在体外明显地受到抑制,抑制的程度和该离子的浓度呈正相关关系。同位素标记方法与传统的显微镜计数方法比较,其结果无明显差异(F=0.41,P>0.05)。此外,同位素标记方法显示出简便、迅速、精确和客观等优点。 Lead is one of the heavy metals that cause environmental pollution. This experiment studied the effect of lead on macrophage immune phagocytosis. The results showed that when the concentration of lead ions was above 10 ~ (-5), the immunophagocytic activity of pulmonary macrophages was significantly inhibited in vitro, and the degree of inhibition was positively correlated with the concentration of the ions. Isotope labeling method compared with the traditional microscope counting method, the results were no significant difference (F = 0.41, P> 0.05). In addition, isotopic labeling methods show the advantages of simplicity, speed, accuracy and objectivity.