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目的:研究清利塞鼻洗液术腔冲洗对内镜鼻窦术后鼻黏膜形态和功能的影响。方法:将Ⅰ型2、3期及Ⅱ型慢性鼻窦患者85例于行内镜鼻窦术后,随机分为清利塞组与对照组;冲洗术腔时清利塞组用清利塞鼻洗液,对照组按传统方法用地塞米松+硫酸庆大霉素;观察其术腔清洁时间、术腔黏膜病变出现时间、上皮化时间以及术后症状改善及疗效等。结果:两组在术腔清洁时间及上皮化时间组间差异有统计学意义(P<0.000 5,0.010.05),1年后临床疗效及术后症状、体征改善清利塞组优于对照组(P<0.05)。结论:清利塞鼻洗液在内镜鼻窦手术后术腔冲洗较传统冲洗方法有显著的优点,值得进一步研究应用。
OBJECTIVE: To study the effects of clear-cut plug nasal washings on morphology and function of nasal mucosa after endoscopic sinus surgery. Methods: Eighty-five patients with stage Ⅰ, 2, 3 and Ⅱ chronic sinusitis undergoing endoscopic sinus surgery were randomly divided into the control group and the QL group. Liquid, the control group by the traditional method of dexamethasone + gentamicin sulfate; observe the cavity cleaning time, mucosal lesions appear time, epithelialization time and postoperative symptoms and efficacy and so on. Results: There was significant difference between the two groups in the time of cleaning the cavity and the time of epithelialization (P <0.0005, 0.01
0.05) After 1 year, the clinical curative effect and postoperative symptom and symptom improvement were better than those in the control group (P <0.05). Conclusion: Cleansing and plug nasal wash after endoscopic sinus surgery than conventional irrigation method has significant advantages, it is worth further study and application.