伤寒和副伤寒是古老的疾病,在病原学、临床及流行病学方面已有较深入的研究,但还有不少问题尚未解决,如带菌者的治疗及近年来出现的抗药菌株等问题。现将国外研究的概况综述如下:一、伤寒杆菌的抗药性问题 (一)目前情况氯(合)霉素自问世后,即成为治疗伤寒的特效药,但自1950年起就发现有散在的 Typhoid fever and paratyphoid fever are ancient diseases, and have been studied thoroughly in etiology, clinical and epidemiological aspects. However, many problems remain unresolved, such as the treatment of carriers and the emergence of drug-resistant strains in recent years . Now the overview of foreign research are summarized as follows: First, the anti-Salmonella bacilli (a) the current situation of chlorine (co) Since the advent of chloroquine, which became the treatment of typhoid fever, but since 1950 found scattered