本文报告一例因α-粒子照射垂体引起ACTH 分泌的突然脱失。过去报导过继发于垂体肿瘤梗塞的垂体分泌衰竭。这可以是辐射治疗引起的垂体肿瘤梗塞有关系,也可能是自发性垂体肿瘤梗塞与辐射治疗巧合。辐射能引起 ACTH 分泌降低,其机制是丘脑下部的损伤或垂体肿瘤梗塞。丘脑下部损伤伴有丘脑下部功能失调如体温变化,情绪波动和其他促激素不足,但本例没有看到这些 This article reports one case of abrupt withdrawal of ACTH due to α-particle irradiation in the pituitary. Pituitary secretion failure secondary to pituitary tumor infarction has been reported in the past. This may be due to a radiation therapy-induced pituitary tumor infarct, or it may be a coincidence of spontaneous pituitary tumor infarction and radiation therapy. Radiation can cause a decrease in ACTH secretion, which is caused by damage to the hypothalamus or pituitary tumors. The hypothalamic injury is associated with dysfunction of the hypothalamus such as changes in body temperature, mood swings, and other hormone-promoting disorders, but this example does not see these