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本文测定36例肝硬化患者的外周血白细胞吞噬功能、血浆纤维连结蛋白(Fn)、内毒素浓度;结果表明,肝硬化患者白细胞吞噬功能和Fn水平明显低于正常对照,这两项指标之间呈明显正相关。肝硬化患者的血浆内毒素浓度明显升高,与白细胞吞噬功能呈明显负相关。提示上述改变可能是肝硬化患者白细胞吞噬功能降低,机体免疫功能减退的主要因素
In this paper, the peripheral blood leukocyte phagocytosis, plasma fibronectin (Fn) and endotoxin concentrations in 36 patients with cirrhosis were measured. The results showed that the leukocyte phagocytosis and Fn levels in cirrhotic patients were significantly lower than those in normal controls Was significantly positive correlation. Plasma endotoxin levels in patients with cirrhosis were significantly increased, and negatively correlated with leukocyte phagocytosis. Suggesting that the above changes may be reduced liver phagocytosis in patients with leukocytosis, the main factor in immune dysfunction