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目的 探讨艾滋病合并卡氏肺孢子虫肺炎 (PCP)的临床特点和诊断方法。方法 对1 999～ 2 0 0 1年经痰聚合酶链反应 (PCR)确诊的 1 2例艾滋病合并PCP进行分析。结果 (1 )合并结核病 4例 ,细菌性肺炎 1例。 (2 )痰PCR阳性 1 2例 ,其中血PCR阳性 9例 ,姬姆萨染色阳性 6例 ,六胺银染色阳性 5例。 (3) 1 2例CD+ 4(5～ 1 55)× 1 0 6 /L ,平均CD+ 4(51± 48)× 1 0 6 /L ;其中CD+ 4<(1 0 0× 1 0 6 ) /L1 0例 (83 % ) ,CD+ 4<(50× 1 0 6 ) /L 9例 (75 % ) ;CD+ 4/CD+ 8:0 .0 1～ 0 .2 9。结论 (1 )PCP是艾滋病晚期常见的合并症 ,常常合并其它机会性感染如结核等。 (2 )痰PCR阳性 +典型的临床表现可以确诊PCP。
Objective To investigate the clinical features and diagnosis of AIDS with Pneumocystis carinii pneumonia (PCP). Methods A total of 12 cases of AIDS complicated with PCP diagnosed by sputum polymerase chain reaction (PCR) from 1999 to 2001 were analyzed. Results (1) Tuberculosis in 4 cases, bacterial pneumonia in 1 case. (2) The sputum PCR positive 12 cases, including blood PCR positive in 9 cases, Giemsa staining in 6 cases, hexamine silver staining in 5 cases. (3) There were 12 CD + 4 (5 ~ 1 55) × 10 6 / L and mean CD + 4 (51 ± 48) × 10 6 / L; CD + 4 <(100 × 10 6) / There were 9 patients (75%) with CD + 4 <(50 × 10 6) / L in L1 0 cases (83%), and CD + 4 / CD + 8: 0. 01 ~ 0. 2 9 cases. Conclusion (1) PCP is a common complication of advanced AIDS, often associated with other opportunistic infections such as tuberculosis. (2) sputum PCR positive + typical clinical manifestations can confirm PCP.