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Objective:To describe high resolution manometry features of a population of symptomatic- patients with Chagas’ disease esophagopathy(CDE).Methods:Sixteen symptomatic dysphagic patients with CDE[mean age(54.81±13.43) years,10 women]were included in this study.All patients underwent a high resolution manometry.Results:Mean lower esophageal sphincter(LES) extension was(3.02±1.17) cm with a mean basal pressure of(15.25±7.00) mmHg.Residual pressure was(14.31±9.19) mmHg.Aperistalsis was found in all 16 patients.Achalasia with minimal esophageal pressurization(type I) was present in 25%of patients and achalasia with esophageal compression(type 2) in 75%,according to the Chicago Classification.Upper esophageal sphincter(UES) mean basal pressure was(97.96±54.22) mmHg with a residual pressure of(12.95±6.42) mmHg.Conclusions:Our results show that LES was hypotensive or normotensive in the majority of the patients.Impaired relaxation was found in a minority of our patients.Aperistalsis was seen in 100%of patients.UES had impaired relaxation in a significant number of patients. Further clinical study is needed to investigate whether manometric features can predict outcomes following the studies of idiopathic achalasia..
Objective: To describe high resolution manometry features of a population of symptomatic-patients with Chagas’ disease esophagopathy (CDE). Methods: Sixteen symptomatic dysphagic patients with CDE [mean age (54.81 ± 13.43) years, 10 women] were included in this study . All patients underwent a high resolution manometry. Results: Mean lower esophageal sphincter (LES) extension was (3.02 ± 1.17) cm with a mean basal pressure of (15.25 ± 7.00) mmHg.Residual pressure was (14.31 ± 9.19) mmHg.Aperistalsis was found in all 16 patients. Achalasia with minimal esophageal pressurization (type I) was present in 25% of patients and achalasia with esophageal compression (type 2) in 75%, according to the Chicago Classification.Upper esophageal sphincter (UES) mean basal pressure was (97.96 ± 54.22) mmHg with a residual pressure of (12.95 ± 6.42) mmHg.Conclusions: Our results show that LES was hypotensive or normotensive in the majority of the patients. Impaired relaxation was found in a minority of our patients. Aperistalsis was s Further clinical study is needed to investigate whether manometric features can predict outcomes the following the studies of idiopathic achalasia .. een in 100% of patients.