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目的:探究与分析紫杉醇联合顺铂治疗乳腺癌肺转移疗效观察。方法:选取我院自2012年4月至2014年4月收治的45例乳腺癌肺转移患者,对其采用紫杉醇联合顺铂治疗,观察该组患者的临床疗效。结果:该组患者经治疗后完全缓解17例(37.78%),部分缓解14例(31.11%),稳定10例(22.22%),进展4例(8.89%),总有效率68.89%。该组患者中出现了4例白细胞水平下降(8.89%),3例血小板下降(6.67%),7例出现了恶心呕吐(15.56%),5例出现肌肉酸痛(11.11%),3例出现了肝功能损害(6.67%),经过对症治疗后可缓解症状。结论:采用紫杉醇联合顺铂治疗乳腺癌肺转移的临床疗效显著,安全性较高,值得推广。
Objective: To investigate and analyze the efficacy of paclitaxel combined with cisplatin in the treatment of lung metastasis of breast cancer. Methods: Forty-five patients with lung metastasis from April 2012 to April 2014 in our hospital were treated with paclitaxel and cisplatin, and the clinical efficacy was observed. Results: Seventeen patients (37.78%) were relieved after treatment, 14 patients (31.11%) were partially relieved, 10 patients (22.22%) were stabilized, 4 patients (8.89%) were progressing, and the total effective rate was 68.89%. There were 4 cases of leukocyte decrease (8.89%), 3 cases of platelet decrease (6.67%), 7 cases of nausea and vomiting (15.56%), 5 cases of muscle soreness (11.11%) and 3 cases of Liver damage (6.67%), after symptomatic treatment can relieve symptoms. Conclusion: The clinical efficacy of paclitaxel combined with cisplatin in the treatment of lung metastasis of breast cancer is significant, safe and worthy of promotion.