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邻居老王退休8年了,原单位组织体检发现下腹腔内有一肿块,一般情况较好,剖腹探查见脏器正常,唯肿块偏大且有粘连,手术摘除送病理检查,提示:转移性腺癌。术后化疗数次,一年后复查,腹腔内肿块消失,但有多个淋巴结肿大,病理切片免疫组化ASP、NSE、PAP、p504S和p63、CK34βE12联合检测才查出原发病灶是前列腺癌。这样的例子还很多,患者癌是查出来了,原发病灶不明,癌来自何处不知道。为什么影像学和生化标志物都不能查出的原发癌,免疫组织化学技术能查出来,免疫组织化学技术真的那么神奇吗?
Neighbor Pharaoh retired for 8 years. The original unit tissue examination revealed a lump in the abdomen. The general condition was good. The caesarean section revealed normal organs. Only the lump was large and had adhesions. Surgical enucleation sent pathological examinations. Tip: metastatic adenocarcinoma . Several times after chemotherapy, one year later, the intra-abdominal mass disappeared, but there were multiple lymphadenopathy. The pathological section immunohistochemistry for the detection of ASP, NSE, PAP, p504S and p63, and CK34βE12 detected the primary lesion as prostate. cancer. There are many examples of this, the patient’s cancer is detected, the original lesion is unknown, the cancer does not know where it came from. Why can’t imaging and biochemical markers detect primary cancers? Can immunohistochemical techniques be detected? Is immunohistochemistry really so magical?