论文部分内容阅读
用大剂量环磷酰胺(4毫克/公斤/日〈首剂加倍〉静脉注射,疗程5天)治疗急性感染性多发性神经炎56例。并以同期应用其它方法治疗的17例,作为对照。结果控制急性期麻痹发展,治疗组平均为3.6天,对照组平均5.6天(P<0.01)。治疗组重型、极重型36例,经治后作气管切开、正压呼吸5例,对照组重型、极重型13例,经治后作气管切开、正压呼吸6例,提示应用大剂量环磷酰胺治疗对改善本病的治疗和预后可能具有积极的临床意义。
Acute infectious polyneuritis was treated with high dose cyclophosphamide (4 mg / kg / day intravenously for 5 days). In the same period, 17 cases were treated by other methods and used as control. Results The development of acute paralysis was controlled by an average of 3.6 days in the treatment group and 5.6 days in the control group (P <0.01). The treatment group of heavy, very heavy in 36 cases, after tracheotomy, positive pressure breathing in 5 cases, the control group of heavy and extremely severe in 13 cases, after tracheostomy, positive pressure breathing in 6 cases, suggesting that the application of large doses Cyclophosphamide treatment may have positive clinical significance in improving the treatment and prognosis of this disease.