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通常认为血清脂蛋白(a)[Lp(a)]的水平增高是动脉粥样硬化的独立危险因素。本研究旨在对不同程度的症状性缺血性脑血管病及不同阶段的颈动脉粥样硬化病人,进行血清Lp(a)水平、载脂蛋白(a)表型及其它脂质参数的完整分析。 265例连续收治的病人(男34％,女66％),平均年龄51±7.4岁,其中TIA 55.8％,可逆性缺血性神经功能缺损28.3％,脑梗塞或多发性脑梗塞15.9％。对照组288例(男30％,女70％),平均年龄51±7.4岁。全部人员均行Lp(a)浓度、载脂蛋白(a)表型、甘油三酯、低密度脂蛋白、高密度脂蛋白及总胆固醇水平的盲码标本测定,同时行颅外颈动脉的
It is generally accepted that increased levels of serum lipoprotein (a) [Lp (a)] are independent risk factors for atherosclerosis. The aim of this study was to investigate the relationship between serum Lp (a) level, apolipoprotein (a) phenotype and other lipid parameters in patients with different grades of symptomatic ischemic cerebrovascular disease and different stages of carotid atherosclerosis analysis. Among 265 consecutive patients (34% males and 66% females), the average age was 51 ± 7.4 years, with TIA 55.8%, reversible ischemic neurological deficits 28.3%, cerebral infarction or multiple cerebral infarction 15.9%. The control group of 288 patients (30% men and 70% women), mean age 51 ± 7.4 years old. All of them were determined by blind code specimens with Lp (a) concentration, apolipoprotein (a) phenotype, triglyceride, low density lipoprotein, high density lipoprotein and total cholesterol. Simultaneous extracranial carotid artery