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目的:总结体外心肺复苏（Extracorporeal cardiopulmonary resuscitation, ECPR）辅助技术用于治疗成人心脏骤停(Cardiac arrest, CA）患者的临床经验。方法:总结分析2015年03月至2019年06月在南京医科大学第一附属医院（江苏省人民医院）行ECPR的31例成年患者的临床资料，按照是否存活出院分为出院存活组(n n=12）及死亡组(n n=19)，分析两组的常规心肺复苏（Conventional cardiopulmonary resuscitation, CCPR）时间、ECMO辅助时间、联合治疗措施。按照CCPR时间分为≤ 60 min、>60 min两组，分析两组自主循环恢复率（Return of spontaneous Circulation, ROSC)、出院存活率和格拉斯哥-匹兹堡脑功能（Cerebral performance classification, CPC)评分。n 结果:存活组CCPR时间显著小于死亡组(n P=0.002)，ECMO辅助时间在两组间差异无统计学意义(n P=0.478)。院内呼吸心搏骤停（In-hospital of cardiac arrest, IHCA）患者和院外呼吸心搏骤停(Out-of-hospital cardiac arrest, OHCA）患者出院存活率差异无统计学意义(n P =0.716)，联合主动脉内球囊反搏（Intra-aortic balloon pump, IABP)治疗患者和无IABP治疗患者出院存活率差异无统计学意义(n P=0.174)，联合持续肾脏替代治疗（Continuous renal replacement therapy, CRRT）患者的出院存活率高于无CRRT治疗患者(n P=0.032)。CCPR ≤ 60min的患者ROSC率及出院存活率均显著高于CCPR >60 min的患者( n P 0.05)。n 结论:ECMO能够为CA患者提供有效的生命支持，提高CA患者存活率，启动ECPR前CCPR时间不建议超过60 min。“,”Objective:To identify the impact of extracorporeal cardiopulmonary resuscitation (ECPR) on neurological outcome and survival in adults with cardiac arrest (CA).Methods:Totally 31 adult patients with ECPR were enrolled from March 2015 to June 2019 in Emergency Department of the First Affiliated Hospital of Nangjing Medical University (Jiangsu People Hospital). Patients were divided to the survival group (n n=12) and death group (n n=19). Duration of conventional cardiopulmonary resuscitation (CCPR) and extracorporeal membrane oxygenation (ECMO) and other mechanical support were compared between groups. Cerebral performance category (CPC) and hospital survival were also evaluated according to the duration of CCPR before ECPR.n Results:The duration of CCPR before ECPR was significantly shorter in the survival group than that in the death group (n P=0.002). Duration of ECMO had no significant difference between the two groups (n P=0.478). The location of CA occurrence had no impact on the hospital survival rate (n P=0.716). ECPR in combination with intra-aortic balloon pump (IABP) also had no impact on the hospital survival rate (n P=0.174), and patients received continuous renal replacement therapy (CRRT) had higher hospital survival than patients without CRRT (n P = 0.032). Patients with CCPR duration ≤ 60 min had higher rates of ROSC and hospital survival (n P <0.001). CPC evaluation showed no difference between the two groups.n Conclusions:ECMO can provide effective life support to CA patients, and improve their survival rates. It is recommended to initiation of ECMO implantation within 60 min after CCPR.