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实验采用D -半乳糖 (D -gal) 80mg·kg 1·d 1小鼠颈部皮下注射 ,造成拟脑老化模型 ,并以古方地黄饮子煎汁灌胃 5 0天 ,观察该方对小鼠生命活动状态 (外观特征 )和学习记忆能力 (跳台法 )的影响作用。实验结果表明 ,地黄饮子可以改善D -gal所致脑衰老小鼠的学习记忆能力。
The experiment was performed with a subcutaneous injection of D-galactose (D-gal) 80 mg·kg 1·d 1 in the neck of mice, resulting in a model of brain aging, and the rats were given intragastric administration of Gufangdihuangzi decoction for 50 days. The effect of rat activity status (appearance characteristics) and learning and memory ability (jumper method). The experimental results show that Dihuang Yinzi can improve the learning and memory ability of brain aging mice induced by D-gal.