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目的:评估口服降糖药血糖控制不佳的2型糖尿病患者联合甘精胰岛素的疗效。方法:选取2012年4月-2012年8月在我院就诊的50例2型糖尿病患者,在使用两种口服降糖药血糖控制仍不达标的基础上联合应用甘精胰岛素治疗,疗程为6个月,观察治疗前后糖化血红蛋白(HbA1c)、空腹血糖(FBG)及体重指数(BMI)的变化。结果:治疗后HbA1c、FBG水平比治疗前明显降低(P<0.01),BMI无明显变化。结论:2型糖尿病在两种口服降糖药治疗仍未达标时联合应用甘精胰岛素可有效降低血糖,不增加体重。
OBJECTIVE: To assess the efficacy of insulin glargine in type 2 diabetic patients with poorly controlled oral hypoglycemic agents. Methods: Fifty patients with type 2 diabetes who were treated in our hospital from April 2012 to August 2012 were treated with insulin glargine on the basis that the two kinds of oral hypoglycemic agents were still not up to standard. The course of treatment was 6 The changes of HbA1c, fasting blood glucose (FBG) and body mass index (BMI) before and after treatment were observed. Results: After treatment, the levels of HbA1c and FBG were significantly lower than those before treatment (P <0.01), but there was no significant change in BMI. Conclusion: Type 2 diabetes combined with insulin glargine when the two oral hypoglycemic agents have not yet reached the standard can effectively reduce blood glucose, do not increase body weight.