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Graves病(GD)是一种器官特异性自身免疫性疾病,其特点是甲状腺内有淋巴细胞的浸润,疾病活动期血循环中存在激活的T细胞和自身抗体,然而,具体的发病机制不详。本文通过对GD患者治疗前后血清CD30水平的测定,探讨CD30分子在GD发病机制中的作用。
Graves’ disease (GD) is an organ-specific autoimmune disease characterized by infiltration of lymphocytes in the thyroid gland and the presence of activated T cells and autoantibodies in the circulatory activity of the disease, however, the exact pathogenesis is unknown. This article through the determination of serum CD30 levels before and after treatment of GD patients to explore the role of CD30 molecules in the pathogenesis of GD.