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探讨海拔５０００ｍ以上地区剧烈运动前后ＲＢＣ──ＳＯＤ活性和血液流变性的变化。５１名平原青年在海拔３７００和５２７０ｍ处进行５公里跑步越野，越野前静息状态和越野后即刻检测ＲＢＣ－ＳＯＤ和６项血液流变学指标。ｔ检验分组比较，结果：静息状态随海拔升高ＲＢＣ－ＳＯＤ活性逐步下降，５２７０ｍ较３７００ｍ下降非常显著（Ｐ＜０．０１），ＨＣＴ和ηｂ逐步增高，亦相差非常显著（Ｐ＜０．０１），ＰＦＣ无显著改变。ＴＫ在３７００ｍ较１４００ｍ增加非常显著（Ｐ＜０．０１），５２７０ｍ较３７００ｍ虽有增加但无统计学意义。ＴＦＬ随海拔升高增加非常显著或增加显著（Ｐ＜０．０１或Ｐ＜０．０５），ＭＳＴ虽有增加但无显著性差异（Ｐ＞０．０５）。越野后即刻较越野前，海拔３７００ｍＲＢＣ－ＳＯＤ、ηｂ、ＴＦＬ显著降低（Ｐ＜０．０５），ＭＳＴ降低非常显著（Ｐ＜０．０１）。海拔５２７０ｍＲＢＣ－ＳＯＤ和ηｂ降低非常显著（Ｐ＜０．０１），其它指标无显著性改变。结论：随海拔升高ＲＢＣ－ＳＯＤ活性降低，血液粘度增高；剧烈运动后ＲＢＣ－ＳＯＤ进一步降低，血液粘度相对降低。
To investigate the changes of RBC-SOD activity and hemorrheology before and after strenuous exercise above 5000m above sea level. Fifty-one plain youngsters were tested for RBC-SOD and six hemorheological parameters immediately after 5km of running at off-road, off-road resting and off-road at 3700 and 5270m above sea level. (P <0.01). HCT and ηb gradually increased, with a significant difference (P <0). The results showed that the activity of RBC-SOD at the resting state declined gradually with elevation. 01), PFC no significant change. TK increased significantly at 1400m compared with 1400m at 3700m (P <0.01), while no significant difference was found between 5270m and 3700m. TFL increased significantly with increasing altitude (P <0.01 or P <0.05), while MST increased but had no significant difference (P> 0.05). Immediately after the off-road, compared with the off-road, the RBC-SOD, ηb and TFL at 3700 m were significantly lower (P <0.05) and MST decreased significantly (P <0.01). The elevation of 5270 mRBC-SOD and ηb at altitude was significant (P <0.01), but no significant change was observed in other indexes. CONCLUSION: RBC-SOD activity decreases and blood viscosity increases with altitude. RBC-SOD is further decreased and blood viscosity is decreased after strenuous exercise.