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目的探讨肝炎后肝硬化患者凝血功能变化的临床诊断、分期价值。方法观察肝炎后肝硬化患者72例,31例慢性乙型肝炎患者作对照。测定凝血酶原时间(PT)、活化部分凝血活酶时间(APTT)、凝血酶时间(TT)、纤维蛋白原(FIB),并按Ch ild-pugh肝功能分级。结果肝炎后肝硬化按Ch ild-pugh肝功能分级PT、APTT、TT逐渐延长,FIB逐渐下降。结论肝炎后肝硬化凝血功能检测有助于肝功能分期、出血严重程度、疗效和预后的评价。
Objective To investigate the clinical diagnosis and staging value of coagulation changes in patients with posthepatitic cirrhosis. Methods 72 patients with posthepatitic cirrhosis and 31 patients with chronic hepatitis B were observed as controls. Prothrombin time (PT), activated partial thromboplastin time (APTT), thrombin time (TT) and fibrinogen (FIB) were measured and graded according to Child-pugh liver function. Results Liver cirrhosis was gradually extended by Child-pugh classification of PT, APTT, TT, and FIB gradually decreased. Conclusion The detection of hepatic cirrhosis coagulation function contributes to the evaluation of liver function staging, bleeding severity, curative effect and prognosis.