适应性细胞保护由Robert[1]在1979年首次提出,在摄入低浓度不足以引起胃黏膜损伤的刺激性物质(温和刺激物)后,消化道黏膜可以耐受较高浓度同类物质或其他刺激性物质的损伤,即弱刺激可增强胃黏膜自身保护作用。胃黏膜长期暴露于各种内、外源性有害因子,适应性保护是其维持上皮表 Adaptive cytoprotection was first proposed by Robert [1] in 1979 after gastrointestinal mucosa can tolerate higher concentrations of congeners or other stimulants (mild stimulants) at concentrations low enough to cause gastric mucosal damage Irritant substances damage, weak stimulation can enhance the protective effect of gastric mucosa itself. Gastric mucosa long-term exposure to a variety of exogenous and harmful factors, adaptive protection is to maintain the epithelial table