一、急性胃黏膜病变的概念和发生机制急性胃黏膜病变(acute gastric mucosal lesion,AGML)又称应激性溃疡,是指机体在各类严重创伤、危重疾病、严重心理应激或各类损害胃黏膜的药物(如阿司匹林、乙醇等)作用下所引起的上消化道急性糜烂、溃疡,主要表现为上消化道出血,少数可并发穿孔。不同病因引起AGML的发生机制不尽相同,一般认为胃酸增加、胃肠黏膜缺血和胃黏膜屏 First, the concept and mechanism of acute gastric mucosal lesions Acute gastric mucosal lesion (AGML), also known as stress ulcer, refers to the body in a variety of serious trauma, critical illness, severe psychological stress or various types of damage Gastric mucosal drugs (such as aspirin, ethanol, etc.) caused by the upper gastrointestinal acute erosion, ulcers, mainly for the upper gastrointestinal bleeding, a small number of concurrent perforation. The causes of AGML caused by different causes vary, generally believed that increased gastric acid, gastrointestinal mucosal ischemia and gastric mucosal screen