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目的:分析药品不良反应(ADR)的特点和发生情况,为临床合理用药提供科学依据。方法:收集我院2010年1月至2011年l2月发生药品不良反应的61例患者的临床资料,对ADR的临床表现、药品种类、用药途径等进行回顾性分析。结果:抗感染药物的不良反应报告51例,占83.6%;由注射液引发的不良反应报告56例,占91.8%;皮肤及其附件不良反应28例,占45.8%。结论:提高临床医护人员的安全用药意识,减少或避免不良反应的发生,保障公众用药安全的关键。
Objective: To analyze the characteristics and occurrence of adverse drug reaction (ADR) and provide a scientific basis for clinical rational drug use. Methods: The clinical data of 61 patients who were admitted to our hospital from January 2010 to January 2011 were analyzed retrospectively. The clinical manifestations, types of drugs and route of administration of ADR were retrospectively analyzed. Results: Adverse reactions of anti-infective drugs were reported in 51 cases (83.6%). Adverse reactions induced by injection were reported in 56 cases (91.8%). Adverse reactions of skin and its accessories were found in 28 cases (45.8%). Conclusion: It is of vital importance to improve the safety awareness of clinical staff, reduce or avoid adverse reactions, and ensure the safety of public medication.