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目的观察苯那普利对Ⅱ型糖尿病患者血糖、胰岛素、胰岛素敏感性的影响。方法３４例口服降糖药治疗的Ⅱ型 糖尿病患者，随机分为两组，治疗组（１８例）加用苯那普利１０ｍｇ每日一次口服，对照组（１７例）不加用药物治疗，两组均连 续观察６０ｄ。用药前后两组均测空腹、餐后２ｈ血糖、胰岛素。结果治疗组，空腹及餐后２ｈ血糖治疗后较治疗前明显降低，差 异显著（Ｐ＜０．０５），胰岛素敏感性增强。结论苯那普利能改善糖尿病患者胰岛素敏感性，降低血糖。
Objective To observe the effects of benazepril on the blood glucose, insulin and insulin sensitivity in type 2 diabetic patients. Methods 34 cases of type 2 diabetes mellitus treated with oral hypoglycemic agents were randomly divided into two groups: the treatment group (18 cases) plus benazepril 10 mg once daily, the control group (17 cases) without drug treatment, Two groups were observed 60 days. Before and after treatment were measured fasting two groups, 2h postprandial blood glucose, insulin. Results The fasting and postprandial blood glucose 2h after treatment were significantly lower than those before treatment (P <0.05), and the insulin sensitivity was enhanced. Conclusion benazapril can improve insulin sensitivity and reduce blood sugar in diabetic patients.