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目的比较乳腺管状腺癌(tubular carcinoma,TC)与浸润性导管癌(invasive ductal carcinoma,IDC)的临床病理特征和预后。方法回顾性分析1996—2009年乳腺癌手术治疗分期为I/II的41例TC患者和分期为I/II的2 568例IDC患者的临床资料,比较两者的临床病理特征和预后。结果与IDC相比较,TC更容易用钼靶X线检测出(71%vs.22.9%,P<0.05),肿物较小,很少有淋巴结浸润(8.6%vs.22.9%,P<0.05)。TC和IDC的复发率分别为7.9%和25.7%(P<0.05),TC的无病生存期显著高于IDC(P<0.05)。结论 TC有着较好的临床病理特征和预后。此外,TC患者与正常人的预期寿命相似,所以辅助性化疗可能不适于作为TC的常规治疗。
Objective To compare the clinicopathological characteristics and prognosis of tubular carcinoma (PTC) with invasive ductal carcinoma (IDC). Methods The clinical data of 41 TC patients with stage I / II of breast cancer and 2 568 IDC patients with stage I / II from 1996 to 2009 were retrospectively analyzed. The clinicopathological features and prognosis of the two groups were compared. Results Compared with IDC, TC was more easily detected by molybdenum target X-ray (71% vs.22.9%, P <0.05), with smaller mass and infiltration of lymph nodes (8.6% vs.22.9%, P <0.05 ). The recurrence rates of TC and IDC were 7.9% and 25.7%, respectively (P <0.05). The disease-free survival of TC was significantly higher than that of IDC (P <0.05). Conclusion TC has a good clinical and pathological features and prognosis. In addition, TC patients and normal life expectancy is similar, so adjuvant chemotherapy may not be suitable as a routine treatment of TC.