二十世纪初 ,流行病学调查发现动脉粥样硬化或其他心血管疾病与感染有一定关系。但是直到 2 0世纪 80年代 ,人们在病理学领域发现了动脉粥样硬化与单核细胞的相关性 ,以及动脉粥样硬化斑块中存在巨噬细胞及淋巴细胞等炎症细胞之后 ,炎症与动脉粥样硬化性疾病的相关性又引起学术 Early twentieth century, epidemiological surveys found that atherosclerosis or other cardiovascular diseases and infections have a certain relationship. However, it was not until the 1980s that the correlation between atherosclerosis and mononuclear cells was found in the field of pathology, and inflammatory cells such as macrophages and lymphocytes were present in atherosclerotic plaques. Relevance of atherosclerotic disease in turn aroused academic