本文报道药物研究的最新进展,部份已经上市,还有的尚处于进一步临床研究阶段,首次报道了用于治疗溃疡病的前列腺素类似物。生物效应调节剂亦是第一次收载。并将胸腺肽制品和肿瘤坏死因子作为这类药物的代表予以介绍。 1.麻醉药和镇痛药近年来,神经肽类的发展越来越引起人们的注意。同时,对肽类镇痛药的认识取得了较大的增长,但直到目前为止,这类药物尚未取得较大的实用意义。其在临床上应用的最大障碍是大多数的此类化合物在全身使用 This article reports the latest advances in drug research, some of which are already on the market, and others that are still in further clinical phase and for the first time report prostaglandin analogues for the treatment of ulcer disease. Biological effect regulator is also included for the first time. Thymic peptide preparations and TNF as a representative of these drugs are described. 1. Narcotics and Analgesics In recent years, the development of neuropeptides has drawn increasing attention. At the same time, the awareness of peptide analgesics has made a big increase, but so far, such drugs have not achieved greater practical significance. Its biggest obstacle in clinical use is that most of these compounds are used systemically