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鼻咽癌是国人头颈区域常见的恶性肿瘤之一,尽管鼻咽癌容易发生远处转移,包括骨骼、肺部、肝脏和远处淋巴结等部位,但继发于鼻咽癌的上矢状窦部位转移十分罕见。我们首次报道一例54岁鼻咽癌男性患者,该患者于放疗和化疗后24个月出现头痛、呕吐、癫痫发作,头颅MRI检查发现右侧额叶占位,肿瘤基底与矢状窦关系密切,临床初步诊断为窦旁脑膜瘤。患者接受了开颅手术治疗,术后组织学和免疫组化结果显示为鼻咽癌,术后随访6个月,患者未再出现局部或远处转移征象。尽管手术切除转移性鼻咽癌并不提倡,但对于部分继发鼻咽癌的颅内窦旁转移性病灶,手术切除仍具有一定的临床价值。
Nasopharyngeal carcinoma is one of the most common malignant tumors in the head and neck area of the Chinese. Although nasopharyngeal carcinoma is prone to distant metastasis, including bone, lung, liver and distant lymph nodes, it is secondary to nasopharyngeal carcinoma Site transfer is very rare. We first reported a 54-year-old male patient with nasopharyngeal carcinoma who had headache, vomiting and seizures 24 months after radiotherapy and chemotherapy and had a cranial MRI examination of the right frontal lobe. The tumor base was closely related to the sagittal sinus, Preliminary clinical diagnosis of sinus meningioma. The patient underwent craniotomy. Postoperative histology and immunohistochemistry showed nasopharyngeal carcinoma. All patients were followed up for 6 months and no local or distant metastasis was observed. Although surgical resection of metastatic nasopharyngeal carcinoma is not advocated, but for some secondary nasopharyngeal carcinoma of the intracranial sinusoid metastases, surgical resection still has some clinical value.