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目的探讨Barrett食管(BE)的临床症状、内镜表现及病理分析。方法收集我院确诊为BE患者的胃镜及病理资料进行回顾性分析。结果 30例BE患者有反酸、胸骨后烧灼感、吞咽不适、胸骨后疼痛等症状。内镜下伴有反流性食管炎、胃溃疡、食管裂孔疝、胆汁反流等,内镜下表现呈环形BE11例(37%),岛状BE12例(40%),舌形7例(23%)。病理检查胃底上皮13例(43%),交界型上皮6例(20%),肠化型上皮11例(37%),其中1例交界型上皮伴轻度异型增生,未发现食管腺癌。结论 BE多发于反流性食管炎者,是食管腺癌的一种癌前病变,BE的早期诊断和治疗对降低食管腺癌的发病率起到了非常关键的作用。
Objective To investigate the clinical symptoms, endoscopic features and pathological analysis of Barrett’s esophagus (BE). Methods Gastroscopy and pathological data of BE patients diagnosed in our hospital were collected retrospectively. Results 30 cases of BE patients had acid reflux, sternal burning sensation, swallowing discomfort, sternum pain and other symptoms. Endoscopic with reflux esophagitis, gastric ulcer, esophageal hiatal hernia, bile reflux, endoscopic showed ring BE11 cases (37%), island BE12 cases (40%), tongue shape in 7 cases twenty three%). Pathological examination included 13 cases (43%) of gastric fundus epithelium, 6 cases of junctional epithelium (20%) and 11 cases of intestinal metaplasia (37%). One case of junctional epithelium with mild dysplasia and no esophageal adenocarcinoma . Conclusions BE is more frequent in patients with reflux esophagitis and is a precancerous lesion of esophageal adenocarcinoma. Early diagnosis and treatment of BE play a crucial role in reducing the incidence of esophageal adenocarcinoma.