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了解临沂市自然人群HBV感染状况。方法整群、分层抽样确定调查对象，抽血检测HBsAg、抗-HBs、抗-HBc、HBeAg。结果自然人群乙肝患病率为48．06／10万，HBSAg、抗-HBS、抗-HBC阳性率及HBV感染率分别为7．11％、23．64％、27．72％和46．59％。年龄上有0～10岁和20～40岁两个感染高峰，40岁后随年龄增高而降低。HBSAg阳性具有明显的家庭聚集性，阳性父母的子女感染HBV的相对危险性成倍递增。阳性者随其滴度增高HBeAg检出率也增高，二者是正相关。抗-HBc、HBV感染率三项指标分布情况与HBSAg的分布相似。结论临沂市属于乙肝中等感染地区，有53．41％的人是易感者，应加强卫生防护。
Understand the status of HBV infection in natural population in Linyi City. Methods Cluster analysis was conducted by stratified sampling to determine the blood samples for HBsAg, anti-HBs, anti-HBc and HBeAg. Results The prevalence of hepatitis B in the natural population was 48.06 / 100 000. The positive rates of HBsAg, anti-HBS, anti-HBC and HBV infection were 7.11%, 23.64%, 27.72% and 46.59 %. There are 0 to 10 years old and 20 to 40 years old two peak infection, 40 years old with age and decreased. HBSAg positive with significant family aggregation, positive parents of children infected with HBV relative risk doubled. Positive with its titer HBeAg detection rate also increased, the two are positively correlated. Anti-HBc, HBV infection rate distribution of three indicators and the distribution of HBSAg similar. Conclusions Linyi City belongs to the moderate hepatitis B infection area, and 53.41% of the people are susceptible. Health protection should be strengthened.