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恶性肿瘤的转移是肿瘤患者死亡的重要原因。尽管迄今的研究工作还没有从根本上解决这个问题,但对转移的基本原理有了许多新的重要的认识。恶性肿瘤的转移是一个复杂的过程。根据多数学者的主张,此过程可分为五个阶段:①肿瘤细胞从原发瘤脱落;②肿瘤细胞对周围组织、血管和淋巴管的浸润;③肿瘤细胞在循环中的运行和滞留;④肿瘤细胞穿出血管、淋巴管;⑤肿瘤细胞的生长、繁殖及转移灶的形成。一、肿瘤细胞从原发瘤脱落Sidebottom 认为它是转移的必备步骤。现已证实,脱落的肿瘤细胞数量与转移的发生成正比。目前认为肿瘤细胞脱落的机理有
Malignant tumor metastasis is an important cause of death of cancer patients. Although the research work so far has not fundamentally solved this problem, there are many new important understandings of the basic principles of the transfer. The metastasis of malignant tumors is a complicated process. According to the opinions of most scholars, this process can be divided into five stages: 1 the shedding of tumor cells from the primary tumor; 2 the infiltration of tumor cells into surrounding tissues, blood vessels and lymphatic vessels; 3 the operation and retention of tumor cells in the circulation; 4 Tumor cells penetrate the blood vessels and lymphatic vessels; 5 tumor cell growth, reproduction, and the formation of metastases. First, the tumor cells fall off from the primary tumor Sidebottom thinks it is an essential step for metastasis. It has been confirmed that the number of shedding tumor cells is directly proportional to the occurrence of metastasis. At present, the mechanism of tumor cell shedding is considered to be