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目的在体外通过实验观察3种中药牙膏对变形链球菌和白色念珠菌的抑菌作用,探讨中药牙膏对龋病及真菌感染的预防作用。方法将两种细菌的国际标准株进行体外培养,取其第三代纯种培养物。采用纸片扩散法来评估中药牙膏的抑菌潜力。结果实验组和对照组牙膏对2种细菌在体外均有明显的抑制其生长的作用,抑菌能力不尽相同(P<0.05)。结论 3种中药牙膏对变形链球菌和白色念珠菌生长可能有抑制作用。
Objective To observe the antibacterial effect of three kinds of traditional Chinese medicine toothpaste on Streptococcus mutans and Candida albicans in vitro and to explore the preventive effect of traditional Chinese medicine toothpaste on dental caries and fungal infections. Methods The two kinds of bacteria international standard strains were cultured in vitro, whichever was the third generation of purebred culture. The paper diffusion method was used to evaluate the antibacterial potential of traditional Chinese toothpaste. Results Both toothpaste of experimental group and control group had significant inhibitory effect on the growth of the two kinds of bacteria in vitro, with different bacteriostatic ability (P <0.05). Conclusion Three kinds of traditional Chinese medicine toothpaste may inhibit the growth of Streptococcus mutans and Candida albicans.