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目的研讨急性逆行性牙髓炎患者运用米诺环素治疗的临床价值。方法从我院2014年10月-2016年10月选取30例急性逆行性牙髓炎患者参与研究试验,并根据随机非盲法分两组(15例/组),Ⅰ组开髓拔髓时接受甲醛甲酚封药,Ⅱ组于根管内封米诺环素,评估该两种治疗方案的临床应用效果。结果方案给药前,两组的叩痛、松动度相比(P>0.05),统计学不成立;给药后,Ⅱ组两项指标检测结果均显著下降,较Ⅰ组优势明显,数据满足(P<0.05),统计学成立。Ⅱ组疼痛缓解时间(9.8±3.1)h,显著比Ⅰ组的(24.8±7.6)h缩短,数据满足(P<0.05),统计学成立。结论对急性逆行性牙髓炎患者实施米诺环素治疗,可有效缓解患者的急性疼痛症状,减小松动度,值得加强推广。
Objective To investigate the clinical value of minocycline in patients with acute retrogressive pulpitis. Methods From October 2014 to October 2016, 30 patients with acute retrograde pulpitis were enrolled in this study. Patients were divided into two groups (15 cases / group) Formaldehyde cresol sealant, Ⅱ group in the root canal sealing minocycline, to evaluate the clinical efficacy of the two treatment options. Results Before the administration, there was no statistically significant difference between the two groups in the percussion pain and the degree of loosening (P> 0.05). After the administration, the test results of both indexes in group Ⅱ were significantly lower than those in group Ⅰ, P <0.05), statistics established. The pain relief time of group Ⅱ (9.8 ± 3.1) h was significantly shorter than that of group Ⅰ (24.8 ± 7.6) h, the data met (P <0.05), and the statistics was established. Conclusion The treatment of minocycline in patients with acute retrogressive pulpitis can effectively relieve the acute pain symptoms and reduce the degree of loosening in patients, which is worth to be promoted.