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目的:评价临床药师对临床不合理用药的药学干预效果,总结干预经验。方法:对比临床药师制度确立前、后相关指标,调取确立前后不合理用药医嘱单与使用记录各500份,对比不合理用药类型分布。结果:确立后,药师参与率90.18%、患者满意率82.78%,高于确立前55.90%、78.75%,不合理用药率2.67%、不良反应率0.40%低于确立前20.59%、1.01%,差异具有统计学意义(P<0.05);确立前品种错误、用量失当、用法适当、适应失当比重分别为40.2%、18.4%、17.4%、24.0%,确立后分别为7.8%、28.2%、32.8%、31.2%,差异具有统计学意义(P<0.01)。结论:药师广泛参与临床一线,干预指导医师开据处方,护士与患者用药,通过巡视、复核督促医护人员提高合理用药意识,还有助于增强患者信心,体现医院专业性。
Objective: To evaluate the pharmacological intervention effect of clinical pharmacists on clinical irrational drug use and summarize the intervention experience. Methods: To compare the indexes before and after the establishment of the clinical pharmacist system before and after the transfer of 500 sets of prescriptions and records of unreasonable prescriptions before and after the establishment of the prescription, and to compare the distribution of irrational drug types. Results: After the establishment, pharmacists’ participation rate was 90.18%, satisfaction rate was 82.78%, higher than 55.90%, 78.75% before establishment, irrational drug use rate 2.67%, adverse reaction rate 0.40% lower than 20.59%, 1.01% before establishment (P <0.05). Before the establishment of the breed, it was wrongly used, the dosage was improper, the usage was appropriate, and the proportion of misconduct was 40.2%, 18.4%, 17.4% and 24.0% respectively, and they were 7.8%, 28.2% and 32.8% , 31.2%, the difference was statistically significant (P <0.01). Conclusion: Pharmacists participate extensively in the clinical frontline. The interventions guide the doctors to prescribe, nurse and treat patients. Through inspection and review, they urge the medical staff to raise awareness of rational drug use. It also helps to enhance patient confidence and reflect the hospital professionalism.