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口腔念珠茵内分泌综合征(CES)定义为慢性粘膜皮肤的念珠茵病(CMC)伴单发或多发的自身免疫性内分泌病,最常见的是甲状旁腺机能减退和(或)阿狄森病。CMC经常是CES的早期表现,多发生于出生后数年内,而内分泌紊乱则在10～15岁以后才出现。本文报告一例典型CES伴发口腔粘膜鳞癌(OMSCC)患者。 一位21岁未婚女性患者,主诉左面颊部急性肿大、疼痛,抗炎治疗无效。既往史:2岁时患甲状旁腺机能减退,8岁患恶性贫血,16岁患阿狄森病,早熟性卵巢功能衰竭,皮肤粘膜指甲念珠菌病,无抽烟、喝酒史。治疗:地塞米松(0.75 mg/d),醋酸氢化考的松(0.1
Oral Candida endocrine syndrome (CES) is defined as chronic inflammatory bowel disease (CMC) associated with single or multiple autoimmune endocrinal disease, most commonly hypoparathyroidism and / or Addison's disease . CMC is often an early manifestation of CES, occurs many years after birth, and endocrine disorders occur after 10 to 15 years of age. This article reports a case of a typical CES with oral squamous cell carcinoma (OMSCC). A 21-year-old woman unmarried, complained of acute enlargement of the left cheek, pain, anti-inflammatory treatment is invalid. Past history: 2-year-old suffering from parathyroid dysfunction, 8-year-old suffering from pernicious anemia, 16-year-old suffering from Addison's disease, precocious ovarian failure, skin and mucosal fingernail candidiasis, no smoking, drinking history. Treatment: dexamethasone (0.75 mg / d), hydrocortisone acetate (0.1