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肝癌发病率在我国占恶性肿瘤第2位,95%以上的原发性肝癌患者是由慢性乙肝表面抗原携带者演变而来的[1]。并且肝癌形成的过程有一定的规律:病毒感染人体后的潜伏状态—急性发病→慢性过程→肝纤维化→肝硬化→肝癌。血清容易获取并易于随时监测,通过检测早期发生变化的蛋白,可能
The incidence of liver cancer in China accounted for the second in malignant tumors, more than 95% of primary liver cancer patients are carriers of chronic hepatitis B surface antigen evolved [1]. And the formation of liver cancer has a certain law of the process: the virus infects the human latent state - acute onset → chronic liver fibrosis → → cirrhosis → liver cancer. Serum is easily accessible and readily monitored, and by detecting proteins that change early, it is possible