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本文报道氨苄青霉素(ABPC)对临床分离菌的抗菌作用以及ABPC栓剂用于小儿呼吸道感染症的临床效果。一、抗菌作用测定了ABPC对1984～1985年由作者分离的金葡菌50株,化脓性链球菌30株,溶血链球菌8株,流感嗜血杆菌17株,大肠杆菌50株,克雷伯氏菌25株(共180株)的最小抑菌浓度(MIC)。结果表明ABPC对化脓性链球菌的MIC在0.024μg/ml以下;对溶血链球菌的MIC为0.05～0.20μg/ml;对88%的流感嗜血杆菌其MIC为0.10～0.78μg/ml,表明ABPC对上述三种菌株有极强的抗菌力。而ABPC对金葡菌、大肠杆菌和克雷白氏菌的抗菌力均差。
This article reports the antibacterial effect of ampicillin (ABPC) on clinical isolates and the clinical efficacy of ABPC suppositories for pediatric respiratory tract infections. First, the antibacterial effect of ABPC determined from 1984 to 1985 by the author isolated Staphylococcus aureus 50, Streptococcus pyogenes 30, hemolytic streptococcus 8, Haemophilus influenzae 17, Escherichia coli 50, Kleber The minimum inhibitory concentration (MIC) of 25 strains of Streptococcus (a total of 180 strains). The results showed that the MIC for ABPC against Streptococcus pyogenes was below 0.024 μg / ml; the MIC for Streptococcus hemolyticus was 0.05 to 0.20 μg / ml; and the MIC for Haemophilus influenzae 88% was 0.10 to 0.78 μg / ml, indicating ABPC against these three strains have a strong antibacterial. ABPC against Staphylococcus aureus, Escherichia coli and Klebsiella were poor antibacterial.