β_2受体激动剂(SABA)是目前临床应用最广泛的支气管舒张剂,通过兴奋气道平滑肌和肥大细胞表面的β_2受体舒张气道,并具有减少肥大细胞和嗜碱性粒细胞脱颗粒、阻止炎性介质释放、降低微血管通透性和增强上皮细胞纤毛功能的作用。根据作用时间β_2受体激动剂分为长效和短效两种,临床最常用的为短效β_2受体激动剂,5~10分钟起效,正是因为其快速起效的特点,也 Beta 2 Receptor Agonist (SABA) is currently the most widely used bronchodilator in clinical applications. It excites airway smooth muscle and the beta 2 receptor on the surface of mast cells to relax the airway and reduces the degranulation of mast cells and basophils. Prevent the release of inflammatory mediators, reduce microvascular permeability and enhance epithelial cell cilia function. According to the role of time β 2 receptor agonists into two kinds of long-acting and short-acting, the most commonly used clinical short-acting β 2 receptor agonists, 5 to 10 minutes onset, precisely because of its rapid onset of the characteristics, but also