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目的探讨非营养性吸吮联合开塞露灌肠对早产儿黄疸治疗的临床效果。方法 80例黄疸早产儿为研究对象,按随机数字表法将其分为对照组和观察组,各40例。对照组早产儿接受常规治疗,观察组早产儿在常规治疗的基础上实施非营养性吸吮联合开塞露灌肠治疗。比较两组早产儿在出生后第3、7、14天的血清胆红素、胃残余奶量、日大便次数及胎粪排尽时间。结果观察组早产儿在出生后第3、7、14天的血清胆红素分别为(137.9±17.0)μmol/L、(128.4±16.1)μmol/L和(84.9±14.8)μmol/L,对照组分别为(160.3±21.9)μmol/L、(151.8±20.8)μmol/L和(105.7±30.1)μmol/L,两组比较,差异均有统计学意义(P均<0.05);观察组早产儿胃残余奶量、日大便次数和胎粪排尽时间分别为(1.1±0.25)ml、(4.4±0.4)次和(90.80±9.9)h,对照组分别为(1.7±0.44)ml、(3.4±0.6)次和(106.29±13.7)h,两组比较,差异均有统计学意义(P均<0.05)。结论在早产儿黄疸的治疗中,非营养性吸吮联合开塞露灌肠处理方案疗效确切,值得在临床上推广应用。
Objective To investigate the clinical effect of non-nutritive sucking combined with Kaifenglu on the treatment of jaundice in premature infants. Methods 80 cases of jaundiced premature children were divided into control group and observation group according to random number table method, each 40 cases. The control group received routine treatment of premature children, the observation group of premature children on the basis of routine treatment of non-nutritive sucking combined with open-celled enema treatment. The serum bilirubin, gastric remnant milk volume, the number of stools and the time of meconium excretion on the 3rd, 7th and 14th day after birth in the two groups were compared. Results Serum bilirubin in preterm infants in the observation group was (137.9 ± 17.0) μmol / L, (128.4 ± 16.1) μmol / L and (84.9 ± 14.8) μmol / L on the 3rd, 7th and 14th day after birth respectively (160.3 ± 21.9) μmol / L, (151.8 ± 20.8) μmol / L and (105.7 ± 30.1) μmol / L respectively), the difference was statistically significant between the two groups (all P <0.05) (1.1 ± 0.25) ml, (4.4 ± 0.4) and (90.80 ± 9.9) h in the stomach, 1.7 ± 0.44 in the control group and ( 3.4 ± 0.6) times and (106.29 ± 13.7) h respectively. The differences between the two groups were statistically significant (all P <0.05). Conclusion In the treatment of jaundice in preterm infants, non-nutritive sucking combined with open-celled enema treatment is effective and worthy of clinical application.