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[目的]探讨汗孔瘤(EP)的临床及病理组织学特点。[方法]回顾性分析22例EP患者的临床病理资料及免疫组化观察、PAS染色。[结果]所有患者临床均误诊,诊断大多数为化脓性肉芽肿、软纤维瘤及疣。肿瘤组织界限清楚,由增生一致的基底细胞样立方形细胞构成,伴灶性导管分化,偶尔形成囊肿,耐淀粉酶PAS阳性,CEA、E-MA导管阳性表达。[结论]EP临床表现多样化,对病程长的红色结节或疣状损害,应考虑到EP的可能,组织学上界限清楚,形态单一的小立方形基底样瘤细胞向皮下生长,整体超过旁边正常皮肤水平线,并出现导管样分化,具有诊断性意义。
[Objective] To investigate the clinical and histopathological features of sweat tumor (EP). [Methods] A retrospective analysis of 22 cases of EP patients with clinical and pathological data and immunohistochemistry, PAS staining. [Results] All patients were clinically misdiagnosed, the majority of diagnosis of pyogenic granuloma, soft fibroids and warts. Tumor tissue boundaries clearly defined by hyperplasia of basal cell-like cubic cells, with focal duct differentiation, and occasionally cyst formation, resistance to amylase PAS positive, CEA, E-MA positive tube. [Conclusion] The clinical manifestations of EP are diversified. For long nodular or verrucous lesions, the possibility of EP should be taken into consideration. Histologically, the cells of small cuboidal basal tumor with single morphology grow subcutaneously and overall exceed Next to normal skin horizontal lines, and catheter-like differentiation, with diagnostic significance.